Inactivation of Prolactin by Human Blood Serum and Plasmin (Fibrinolysin)

Abstract
Ovine prolactin (7.5 IU) was incubated for 2 hours at 37[degree]C with human blood serum and human fibrinolysin. Moderate decreases of prolactin activity occurred after incubation in 10% serum, and somewhat greater losses occurred when incubated in 45% serum. Fibrinolysin caused almost complete inactivation of prolactin.