Elevated manganese levels associated with dementia and extrapyramidal signs
- 1 March 1977
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 27 (3) , 213
- https://doi.org/10.1212/wnl.27.3.213
Abstract
In a patient with elevated manganese levels, dementia, and an extrapyramidal syndrome, brain biopsy showed numerous neuritic plaques and neurofibrillary tangles typical of Alzheimer9s disease. Manganese was elevated beyond toxic levels in serum, hair, urine, feces, and brain. The possible relationship of elevated manganese levels, dementia, and the extrapyramidal syndrome warrants further studies of similar cases.This publication has 3 references indexed in Scilit:
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- Manganese in Health and DiseasePhysiological Reviews, 1958