Human Na+, K+-ATPase genes
Open Access
- 6 November 1989
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 257 (2) , 439-442
- https://doi.org/10.1016/0014-5793(89)81591-1
Abstract
The existence of a chromosome gene family containing at least one gene and one pseudogene was shown for the Na+,K+‐ATPase β‐subunit. A partial structure of the βI‐gene was determined, the coding part of which was completely homologous to cDNA of the Na+ K+‐ATPase βI‐subunit from HeLa cells [8]. The region encoding the putative protein transmembrane domain was shown to be bordered by two introns. The structure of a pseudogene (βψ) was determined. This pseudogene is processed and contains multiple stop codons. Its homology to the βI‐subunit cDNA from HeLa cells is about 88%.Keywords
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