Abstract
Previous reports on powerful growth-stimulating effects of a mouse submaxillary gland protein fraction (NGF) on certain peripheral ganglia have been confirmed. Norepinephrine content of enlarged sympathetic ganglia in NGF-treated mice increased proportionate to tissue mass (3- to 4-fold). Norepinephrine concentrations of the heart and submaxiUary gland increased about 2-fold in NGF-treated mice, while no significant increases were detected in brain, adrenal gland, spleen and liver.