Expression of high affinity iron uptake systems by clinical isolates of Klebsiella
Open Access
- 1 November 1987
- journal article
- Published by Oxford University Press (OUP) in FEMS Microbiology Letters
- Vol. 44 (3) , 407-412
- https://doi.org/10.1016/0378-1097(87)90356-9
Abstract
Seventeen isolates of Klebsiella aerogenes, K. pneumoniae, K. oxytocum and K. edwardsii were examined for their ability to express iron-regulated outer membrane proteins (IROMPs) and high affinity iron-chelating agents (siderophores). In response to iron deprivation, all strains induced at least 4 IROMPs in the approximate Mr range 70 000–85 000 and the phenolate siderophore enterobactin. Six strains also produced the hydroxamate siderophore aerobactin. The Klebsiella enterobactin receptor was identified as an 81 000 Mr iron-repressible outer membrane (OM) protein which appears to be highly conserved and shows considerable antigenic homology with that of Escherichia coli.Keywords
This publication has 0 references indexed in Scilit: