Incontinentia Pigmenti and Defective Neutrophil Chemotaxis

Abstract
• A child with incontinentia pigmenti and chronic erythema multiforme had recurrent bacterial infections. Greatly elevated serum IgE was found. In addition, the patient's neutrophils showed essentially no chemotaxis towardStaphylococcus aureus, Escherichia coli, orPseudomonas aeruginosain either patient or control serum. Neutrophil phagocytosis and killing function were normal. (Arch Dermatol111:1603-1605, 1975)

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