Poliovirus Crystals within the Endoplasmic Reticulum of Endothelial and Mononuclear Cells in the Monkey Spinal Cord
- 21 March 1969
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 163 (3873) , 1336-1337
- https://doi.org/10.1126/science.163.3873.1336
Abstract
The lumbar motor columns of a cynomolgus monkey that had become tetraplegic after experimental infection with a highly virulent strain of type 3 poliovirus were examined by electron microscopy. Crystalline aggregates of poliovirus occurred within the endoplasmic reticulum of endothelial cells as well as of mononuclear inflammatory cells. This finding suggests that the endoplasmic reticulum might be much more involved in poliovirus multiplication than has been previously supposed.Keywords
This publication has 12 references indexed in Scilit:
- Replication of poliovirus in HeLa cells: Electron microscopic observationsVirology, 1965
- Electron microscopic study of the formation of poliovirusVirology, 1965
- A cytoplasmic structure involved in the synthesis and assembly of poliovirus componentsJournal of Molecular Biology, 1964
- A cytoplasmic particulate involved in poliovirus synthesisVirology, 1963
- Formation of poliovirus in monkey kidney tissue culture cellsVirology, 1962
- Micromorphology of FL cells infected with polio and Coxsackie virusesVirology, 1961
- Indications of multiplication of porcine enterovirus within the intracellular canalicular systemVirology, 1960
- Electron microscopic demonstration of intracellular poliovirus crystalsExperimental Cell Research, 1959
- Macrocrystalline patterns of closely packed poliovirus particles in ultrathin sectionsJournal of Ultrastructure Research, 1958
- The structure of crystals of purified Mahoney poliovirusBiochimica et Biophysica Acta, 1958