Effect of Cooling and of Smoking Tobacco upon the Blood Flow of Reactive Hyperemia of the Foot

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Abstract
Tobacco smoking and body cooling have been shown to decrease the "resting" blood flow to the foot. The present study was designed to determine whether either of these 2 stimuli also affects the increased blood flow that follows a period of ischemia (reactive hyperemia). Blood flows to the foot were measured in subjects with and without vascular disease by the venous occlusion, water plethysmographic method in a warm and a cool environment before and during smoking. Patients with bilaterally and unilaterally sympathectomized limbs were also studied to determine the mechanism of the observed responses.