Retrovirus antigens in brains of mice with scrapie- and murine leukemia virus-induced spongiform encephalopathy
- 1 October 1982
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 38 (1) , 396-398
- https://doi.org/10.1128/iai.38.1.396-398.1982
Abstract
Wild mouse ecotropic virus-induced spongiform encephalomyelopathy pathologically similar to scrapie was associated with the expression of retrovirus antigens in mouse brains. However, scrapie-infected mice with spongiform encephalopathy showed no increased expression of retrovirus antigens in brain. Thus, the pathogenesis of the scrapie spongiform lesion does not appear to involve activation of endogenous retrovirus.This publication has 23 references indexed in Scilit:
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