Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism
- 1 May 2004
- journal article
- review article
- Published by Elsevier in Drug Discovery Today
- Vol. 9 (10) , 442-449
- https://doi.org/10.1016/s1359-6446(04)03061-2
Abstract
No abstract availableKeywords
This publication has 59 references indexed in Scilit:
- Impact of Drug Transporter Studies on Drug Discovery and DevelopmentPharmacological Reviews, 2003
- Cytochromes P450, Drugs, and DiseasesMolecular Interventions, 2003
- SXR, a novel steroid and xenobioticsensing nuclear receptorGenes & Development, 1998
- Identification of a human nuclear receptor defines a new signaling pathway for CYP 3 A inductionProceedings of the National Academy of Sciences, 1998
- The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B GeneMolecular and Cellular Biology, 1998
- Androstane metabolites bind to and deactivate the nuclear receptor CAR-βNature, 1998
- The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.Journal of Clinical Investigation, 1998
- An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling PathwayCell, 1998
- The RXR heterodimers and orphan receptorsPublished by Elsevier ,1995
- A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements.Molecular and Cellular Biology, 1994