A novel arsenical in clam kidney identified by liquid chromatography/electrospray ionisation mass spectrometry
- 13 August 2001
- journal article
- research article
- Published by Wiley in Rapid Communications in Mass Spectrometry
- Vol. 15 (17) , 1641-1646
- https://doi.org/10.1002/rcm.420
Abstract
Kidneys of clams of the genus Tridacna accumulate metabolic products from symbiotic unicellular algae that grow in the mantles of the clams. These metabolites include organoarsenic compounds that are biosynthesised by algae from arsenate in seawater. The arsenic compounds in aqueous extracts of the kidney of the giant clam T. derasa were investigated by liquid chromatography/electrospray ionisation mass spectrometry. About 50% of the water-soluble arsenic was present as dimethylarsinoylribosides and dimethylarsinate which are common algal metabolites. The major compound in the kidney (50% of water-soluble arsenic) was identified as a 5-dimethylarsinoyl-2,3,4-trihydroxycarboxylic acid, a new natural product. Copyright © 2001 John Wiley & Sons, Ltd.Keywords
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