Dopamine-induced relaxation in human pulmonary arteries

Abstract
Dose-dependent relaxations were induced by dopamine in human pulmonary arteries that had been contracted with prostaglandin F without α-adrenergic blocking agents. The dopamine-induced relaxation was inhibited by haloperidol and fluphenazine, but not by domperidone, suggesting that this relaxation was mediated via DA1 receptors.