Determination of Caffeine in Analgesic Formulations Using the Apparent Content Curves Method
- 1 September 1994
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 27 (12) , 2317-2330
- https://doi.org/10.1080/00032719408005985
Abstract
The determination of caffeine by UV spectroscopy in pharmaceutical samples, containing different compounds which provide spectral interferences as aspirin, paracetamol, chlorfeniramine or propylphenazone, is carried out. The proposed procedure is based on the apparent content curves method in order to resolve binary, ternary and multicomponent mixtures. Results obtained are, in all cases, in agreement with contents found by a HPLC procedure used as reference method.Keywords
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