Viscosity and Iron Deficiency in Treated Polycythaemia
- 1 September 1981
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 49 (1) , 123-127
- https://doi.org/10.1111/j.1365-2141.1981.tb07205.x
Abstract
An in vitro study of the effect of red-cell changes due to Fe deficiency on whole-blood viscosity was made on samples from patients with polycythemia treated by venesection. When the PCV [packed cell volume] of the samples was adjusted to a standard value of 0.45, whole-blood viscosity was unrelated to decreasing MCH [mean corpuscular Hb]. When samples were adjusted to a standard Hb concentration of 14 g/dl, whole-blood viscosity rose exponentially with decreasing MCH. This increase in whole-blood viscosity was a function of the increasing PCV that accompanies the falling MCH at this standard Hb value. In polycythemia not due to hypoxia, hyperviscosity can be satisfactorily corrected by venesection controlled by monitoring the PCV alone. Other considerations may apply in hypoxic polycythemia and these are discussed.This publication has 5 references indexed in Scilit:
- Blood rheology.Journal of Clinical Pathology, 1980
- Plasma and whole blood viscosity in treated primary polycythaemiaClinical and Laboratory Haematology, 1980
- The Effect of Iron Deficiency on Whole Blood Viscosity in Polycythaemic PatientsBritish Journal of Haematology, 1979
- VASCULAR OCCLUSIVE EPISODES AND VENOUS HÆMATOCRIT IN PRIMARY PROLIFERATIVE POLYCYTHÆMLXPublished by Elsevier ,1978
- Studies on the hemodynamic importance of blood viscosityThe Journal of Thoracic and Cardiovascular Surgery, 1965