Successful treatment of acquired haemophilia with prednisolone therapy
- 21 November 2003
- journal article
- case report
- Published by Wiley in Haemophilia
- Vol. 9 (6) , 741-743
- https://doi.org/10.1046/j.1351-8216.2003.00830.x
Abstract
Summary. Acquired hemophilia is a rare, life threatening coagulopathy in adults caused by the development of autoantibodies against to factor VIII. No general consensus exists on the best therapeutic approach. We report here a case that presented with extensive cutaneous and mucosal bleedings due to factor VIII inhibitors and treated successfully with steroid therapy alone but complicated with a life threatening thromboembolic attack during her follow up. In conclusion, corticosteroids are “cost effective therapy” associated with high inhibitor elimination rates and although recurrence of inhibitor in a patient with factor VIII inhibitor is an expected clinical situation thrombosis risk should also be considered.Keywords
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