Treatment of recalcitrant orogenital ulceration of Behcet's syndrome with infliximab

Abstract
Sir, The recurrent oral and genital ulceration of Behçet's syndrome (BS) can be very distressing and is associated with considerable physical and psychological morbidity. We describe a case of Behçet's syndrome in a 65‐yr‐old woman whose orogenital ulceration was unresponsive to a wide range of topical and systemic treatments. Treatment with infliximab, a chimeric anti‐tumour necrosis factor α (anti‐TNF‐α) monoclonal antibody, in May 2000 resulted in the patient being free from ulceration for the first time in 10 yr.

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