Therapy of a Murine Model of Pediatric Brain Tumors using a Herpes Simplex Virus Type-1 ICP34.5 Mutant and Demonstration of Viral Replication within the CNS

Abstract
To develop improved therapies for medulloblastoma, we studied the ability of a neuroattenuated HSV-1 ICP34.5 mutant (variant-1716) to replicate withi

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