Pyridazinodiazepines as a High-Affinity, P₂−P₃Peptidomimetic Class of Interleukin-1β-Converting Enzyme Inhibitor

This publication has 9 references indexed in Scilit:

• α-((Tetronoyl)oxy)- and α-((tetramoyl)oxy)methyl ketone inhibitors of the interleukin-1β converting enzyme (ICE)
  Bioorganic & Medicinal Chemistry Letters, 1997
• First Examples of Peptidomimetic Inhibitors of Interleukin-1β Converting Enzyme
  Journal of Medicinal Chemistry, 1996
• Effects of topical antiinflammatory agents on Freund's adjuvant-induced skin lesions in rats
  Inflammation Research, 1995
• Preparation and evaluation of peptidic aspartyl hemiacetals as reversible inhibitors of interleukin‐l β converting enzyme (ICE)
  International Journal of Peptide and Protein Research, 1994
• Bicyclic turned dipeptide (BTD) as a β-turn mimetic; its design, synthesis and incorporation into bioactive peptides
  Tetrahedron, 1993
• A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes
  Nature, 1992
• IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1 beta precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha.
  The Journal of Immunology, 1991
• Substrate specificity of the protease that processes human interleukin-1 beta.
  Journal of Biological Chemistry, 1990
• Protected lactam-bridged dipeptides for use as conformational constraints in peptides
  The Journal of Organic Chemistry, 1982