BRAIN 5-HYDROXYTRYPTAMINE, 5-HYDR0XYTRYPT0PHAN. DECARBOXYLASE, AND MONOAMINE OXIDASE OF NORMAL, THYROID-FED, AND PROPYLTHIOURACIL-FED MALE AND FEMALE RATS1
- 1 December 1961
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 69 (6) , 1099-1102
- https://doi.org/10.1210/endo-69-6-1099
Abstract
Male and female Wistar rats (125–175 gm.) were fed for 21 days ad libitum diets of a meal containing 0.15% strong desiccated thyroid, 0.15% propylthiouracil, or meal alone. Neither thyroid nor propylthiouracil feeding significantly altered brain 5-hydroxytryptamine, 5-hydroxytryptophan decarboxylase, or monoamine oxidase in either sex. Female rats were found to possess significantly greater 5-hydroxytryptophane dcearboxylase and monoamine oxidase activities than the males. No sex difference was noted in brain 5-hydroxytryptamine content.Keywords
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