Hb CAPA OR α294(G1)ASP→GLYβ2, A Mildly Unstable Variant with an A↠G (Gac↠Ggc) Mutation in Cown 94 of the α1-Globin Gene
- 1 January 1994
- journal article
- research article
- Published by Taylor & Francis in Hemoglobin
- Vol. 18 (1) , 57-60
- https://doi.org/10.3109/03630269409014146
Abstract
A 28-year-old female from the city of Kars in Turkey was treated for a chronic iron deficiency anemia with oral iron. During the clinical evaluation a slowly moving hemoglobin (Hb) variant was detected which migrated about like Hb F in alkaline electrophoresis and like Hb S in agar electrophoresis at pH 6.2. The variant appeared mildly unstable in a heat denaturation test (60°C) but the isopropanol stability test was questionably positive (for methodology, see Ref. 1).Keywords
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