Multicenter clinical placebo‐controlled study with acetyl‐l‐carnitine (LAC) in the treatment of mildly demented elderly patients
- 1 January 1988
- journal article
- research article
- Published by Wiley in Drug Development Research
- Vol. 14 (3-4) , 213-216
- https://doi.org/10.1002/ddr.430140310
Abstract
Acetyl‐l‐carnitine (LAC) was administered for 3 months, 2 g/daily, to 30 elderly patients with mild mental deterioration. Results were compared to those of a homogeneous control group of 28 patients treated with placebo. The study was carried out according to a double‐blind, randomized methodology. A complete battery of rating scales and psychometric tests was used for for evaluating the modifications induced by either drug or placebo. The statistical evaluation of results showed a sufficient clear efficacy of the drug studied: results from patients on LAC were frequently different from those receiving placebo. Therefore, LAC must be taken into consideration as a useful drug for the global treatment of demented elderly patients.Keywords
This publication has 1 reference indexed in Scilit:
- The Action of Carnitines on Cortical NeuronsCanadian Journal of Physiology and Pharmacology, 1971