Isolation of Human Serum Alpha-2 HS Glycoprotein

Abstract
Alpha-2 HS glycoprotein was obtained in an almost pure state from normal human serum, by ion exchange chromatography followed by curtain electrophoresis, gel filtration and ammonium sulfate precipitation. Alpha-2 HS glycoprotein has a sedimentation coefficient of 3.5 S, and an approximate molecular weight of 49,000 Dal tons. Purified α2HS glycoprotein enhances phagocytosis and may be the human homologue of rat α2 opsonic protein.

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