DNA Gyrase and Topoisomerase IV Mutations in Clinical Isolates of Ureaplasma spp. and Mycoplasma hominis Resistant to Fluoroquinolones
Open Access
- 1 October 2003
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 47 (10) , 3323-3325
- https://doi.org/10.1128/aac.47.10.3323-3325.2003
Abstract
Twelve clinical isolates of Ureaplasma spp. and one isolate of Mycoplasma hominis were examined for resistance to fluoroquinolones. Previously described mutations at positions 83 and 95 in GyrA (Escherichia coli numbering) and positions 80 and 87 in ParC were found. Unusual alterations were described at positions ParC 123 and 134.Keywords
This publication has 15 references indexed in Scilit:
- Proposal of Ureaplasma parvum sp. nov. and emended description of Ureaplasma urealyticum (Shepard et al. 1974) Robertson et al. 2001.International Journal of Systematic and Evolutionary Microbiology, 2002
- Characterization of Mutations in DNA Gyrase and Topoisomerase IV Involved in Quinolone Resistance of Mycoplasma gallisepticum Mutants Obtained In VitroAntimicrobial Agents and Chemotherapy, 2002
- Mycoplasmas of HumansPublished by Springer Nature ,2002
- Arthrite septique à Ureaplasma urealyticum : à propos d'un casMedecine Et Maladies Infectieuses, 2001
- Mechanisms and Frequency of Resistance to Premafloxacin in Staphylococcus aureus : Novel Mutations Suggest Novel Drug-Target InteractionsAntimicrobial Agents and Chemotherapy, 2000
- Fluoroquinolone Resistance in Clinical Isolates of Streptococcus pneumoniae : Contributions of Type II Topoisomerase Mutations and Efflux to Levels of ResistanceAntimicrobial Agents and Chemotherapy, 2000
- In Vitro Activity of Trovafloxacin Compared to Those of Five Antimicrobials against Mycoplasmas Including Mycoplasma hominis and Ureaplasma urealyticum Fluoroquinolone-Resistant Isolates That Have Been Genetically CharacterizedAntimicrobial Agents and Chemotherapy, 2000
- Mutations in the gyrA , parC , and parE Genes Associated with Fluoroquinolone Resistance in Clinical Isolates of Mycoplasma hominisAntimicrobial Agents and Chemotherapy, 1999
- Alterations in Topoisomerase IV and DNA Gyrase in Quinolone-Resistant Mutants of Mycoplasma hominis Obtained In VitroAntimicrobial Agents and Chemotherapy, 1998
- Bacterial Topoisomerases, Anti‐Topoisomerases, and Anti‐Topoisomerase ResistanceClinical Infectious Diseases, 1998