Hepatic lymphoma in cyclosporine-treated transplant recipients: sonographic and CT findings

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Abstract
The purpose of this study was to determine the CT and sonographic features of hepatic lymphoma developing in organ transplant recipients taking cyclosporine. The four patients included in the study had non-Hodgkin lymphoma. Two of the cases were primary, with no associated lymphadenopathy or extrahepatic lesions. The hepatic lymphomas were characterized by multiple low-density areas on CT scans and hypoechoic areas on sonograms. In three of the four patients, the lesions regressed after the cyclosporine dosage was reduced. We conclude that in cyclosporine-treated organ transplant recipients, hepatic lymphoma should be considered in the differential diagnosis of hepatic lesions with or without lymphadenopathy when multiple low-density lesions are shown by CT and hypoechoic lesions are shown by sonography.