The development of novel ninhydrin analogues
- 11 February 2005
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Chemical Society Reviews
- Vol. 34 (5) , 408-417
- https://doi.org/10.1039/b315496n
Abstract
Following its discovery by Siegfried Ruhemann in 1910, ninhydrin rapidly became a practical analytical tool. In 1954 it was found to be an important reagent to develop fingerprints on porous surfaces. Since its use in forensic chemistry, many efforts have focused on improving the reagent. Many of the shortcomings of ninhydrin have been met by the synthesis of a variety of ninhydrin analogues. This tutorial review provides a short introduction to ninhydrin and highlights the different synthetic approaches used in the development of analogues for the detection of latent fingerprints.Keywords
This publication has 33 references indexed in Scilit:
- Applications of the Ninhydrin Reaction for Analysis of Amino Acids, Peptides, and Proteins to Agricultural and Biomedical SciencesJournal of Agricultural and Food Chemistry, 2004
- Synthetic studies of novel ninhydrin analogsCanadian Journal of Chemistry, 2001
- Novel approaches toward ninhydrin analogsTetrahedron Letters, 1994
- Ninhydrin and ninhydrin analogs. Syntheses and applicationsTetrahedron, 1991
- X=Y-ZH compounds as potential 1,3-Dipoles. Part 281,2 the iminium ion route to azomethine ylides. background and reaction of amines with bifunctional ketones.Tetrahedron, 1990
- Cycloaddition reaction relevant to the mechanism of the ninhydrin reaction. X-Ray crystal structure of protonated Ruhemann's purple, a stable 1,3-dipoleJournal of the Chemical Society, Chemical Communications, 1986
- Stoichiometry of formation of Ruhemann's purple in the ninhydrin reactionBioorganic Chemistry, 1974
- .beta.-Keto sulfoxides. V. Condensation of dimethyl sulfoxide and dimethyl sulfone with dibasic estersThe Journal of Organic Chemistry, 1969
- Detection of Fingerprints by the Ninhydrin ReactionNature, 1954
- CXXXII.—Cyclic di- and tri-ketonesJournal of the Chemical Society, Transactions, 1910