High-Density Nucleoside Analog Probe Arrays for Enhanced Hybridization
- 1 June 1999
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 18 (6-7) , 1293-1295
- https://doi.org/10.1080/07328319908044695
Abstract
DNA probe arrays were synthesized with analogs of 2,6-diaminopurine and 2′-O-methyl-thymidine in place of A and T. AT-rich GeneChip® test arrays containing 14-mer or 20-mer analog probes improved hybridization to fluorescently-labeled RNA sequences under stringent conditions.Keywords
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