A Test of the Immunoreactive Theory of Selective Male Affliction

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Abstract
A survey of the charts of 576 children evaluated at the Child Study Center of the University of Arkansas for Medical Sciences revealed, as expected, the phenomenon of selective male affliction in five common diagnostic groups. Evidence in support of Gualtieri and Hick's (1985) immunoreactive theory of selective male affliction (IMRT) was mixed. That is, the IMRT predicts that in diagnostic groups where there is selective male affliction, male probands will more frequently have antecedent brothers than female probands, which was not confirmed. However, males in diagnostic groups implicating primary cognitive dysfunction were found to have antecedent brothers more frequently than males in diagnostic groups showing behavioral and emotional adjustment disorders. Males with diagnoses of attention or anxiety/affective disorders were more frequently firstborn than those with cognitive disorders.

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