Differences in Secretory Excitability between Short and Long Adrenergic Neurons: Comparison of 3H‐Noradrenaline Secretion Evoked by Field Stimulation of Guinea‐Pig Vas Deferens and Human Blood Vessels
- 1 June 1977
- journal article
- research article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 100 (2) , 264-266
- https://doi.org/10.1111/j.1748-1716.1977.tb05947.x
Abstract
On comparing the secretion of noradrenaline (NA) evoked by electrical field stimulation of the ‘short’ adrenergic nerves of guinea‐pig isolated vas deferens (Sjöstrand 1962) with that evoked by similar stimulation of the ‘long’ adrenergic nerves of human isolated omental blood vessels, using identical experimental conditions, it was found that the two types of nerve differ markedly in ‘secretory excitability’. While it was possible to adjust the strength and/or duration of stimulus shocks to a level causing a well‐defined maximum in 3H‐NA output from the human vasomotor nerves, no such ‘supramaximal’ level could be reached in the nerves of guinea‐pig vas deferens.This publication has 3 references indexed in Scilit:
- Do potassium ions released from nerve modulate the sensitivity to transmitter in ‘close’ neuro-effector junctions of the vas deferens?Neuroscience, 1977
- β2-Adrenoceptors Facilitating Noradrenaline Secretion from Human Vasoconstrictor NervesActa Physiologica Scandinavica, 1976
- Inhibition by Ganglionic Blocking Agents of the Motor Response of the Isolated Guinea‐Pig Vas Deferens to Hypogastric Nerve StimulationActa Physiologica Scandinavica, 1962