Isoelastic Polyurethane Prosthesis for Segmental Trachea Replacement in Beagle Dogs

Abstract
Porous polyurethane (nonwoven) was used for the development of tracheal prosthesis, which-in a special testing design-was adapted to shape and biome-chanic properties of the natural organ. This prosthesis was implanted into 19 beagle dogs using inverted, everted, and end-to-end anastomosis. Insufficiency of the anastomosis or infection was observed in the everted and end-to-end anastomosis, whereas the inverted anastomosis showed complete incorporation into surrounding tissue of the porous prosthesis but was complicated by airway obstruction due to anastomosis granuloma.

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