METHYL HYDANTOIN (MESANTOIN) IN THE TREATMENT OF EPILEPSY*
- 1 August 1948
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Nervous & Mental Disease
- Vol. 108 (2) , 118-128
- https://doi.org/10.1097/00005053-194810820-00004
Abstract
The anticonvulsant drug, 3-methyl-5,5-phenylethylhydantoin (mesantoin, or methyl hydantoin) was tried for periods as long as 8 mos. in the treatment of 20 patients with epilepsy. The avg. dose was 0.1 gm. 3 times daily. In 11 patients with grand mal, mesantoin was more effective than previously used drugs in 7 cases. The number of petit mal attacks was decreased in each of the 16 patients suffering from this condition. Untoward effects consisted of a dermatitis in 3 cases, gastritis in 1, toxic psychosis in 1, and stimulatory effects (elation, insomnia, etc.) in 10 cases. Prowsiness, gum hyperplasia, or depression of the white count was not encountered.Keywords
This publication has 1 reference indexed in Scilit:
- EPILEPSYAmerican Journal of Psychiatry, 1946