THE EFFECT OF OOPHORECTOMY ON PLASMA OESTRONE AND ANDROSTENEDIONE LEVELS IN THE RAT
- 1 July 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 88 (3) , 562-566
- https://doi.org/10.1530/acta.0.0880562
Abstract
Plasma estrone and androstenedione levels were measured in oophorectomized and sham-operated rats by means of radioimmunoassay. The mean estrone level in the oophorectomized animals was approximately 2/3 of that in the intact animals while the androstenedione levels were about half of those in the intact rats. A direct relationship was observed between the plasma estrone and androstenedione levels in the control animals and to a lesser extent in the oophorectomized animals. Approximately 50% of circulating androstenedione and 30% of circulating estrone originate in the ovaries in the female adult rat.This publication has 1 reference indexed in Scilit:
- Mammalian ReproductionNature, 1969