Immunodeficiency Disorders

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Abstract
Malformations can be caused by many factors, both genetic and environmental. Conceptually, it has been easier to imagine a dominant or recessive gene or an extra chromosome or a drug taken by the mother as a cause of a malformation than it has been to conceptualize the process known as multifactorial inheritance. In this process of multifactorial inheritance both genetic and environmental factors combine to cause a structural malformation. Although the process may not be as easy to conceptualize, malformations due to multifactorial inheritance are much more common than those attributed to other recognized etiologies.

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