A Rapid Procedure to Identify Newborn Transgenic Mice
- 1 May 1989
- journal article
- research article
- Published by Mary Ann Liebert Inc in DNA
- Vol. 8 (4) , 297-299
- https://doi.org/10.1089/dna.1.1989.8.297
Abstract
We have developed a rapid procedure to identify newborn transgenic mice containing foreign genetic material in their genome. The protocol involves collagenase digestion of a small amount of tail tissue which can be taken very early after birth, phenol and chloroform extraction, polymerase chain reaction, and polyacrylamide gel electrophoresis. The entire procedure, from tissue biopsy to final results, can be completed in 1 day.This publication has 5 references indexed in Scilit:
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