The Heat Production of Pancreatic β-Cells Stimulated by Glucose
- 1 February 1975
- journal article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 93 (2) , 179-183
- https://doi.org/10.1111/j.1748-1716.1975.tb05807.x
Abstract
A recently developed batch microcalorimeter was used for studying heat production in beta-cell-rich pancreatic islets isolated from obese-hyperglycemic mice. In the absence of glucose, the rate of heat production was 50 nW/islet increasing to 90 nW/islet when the islets were exposed to 20 mM glucose. The data obtained are consistent with an increase in the caloric value of oxygen with glucose concentration, as might be expected when the beta-cells utilize proportionally more carbohydrate as a source of energy.Keywords
This publication has 11 references indexed in Scilit:
- The preparation of, and studies on, free cell suspensions from mouse pancreatic isletsDiabetologia, 1974
- A Modified Flow Microcalorimeter Adapted for the Study of Human Leucocyte PhagocytosisScandinavian Journal of Clinical and Laboratory Investigation, 1973
- Dissociation of the insulin releasing and the metabolic functions of hexoses in islets of langerhansBiochemical and Biophysical Research Communications, 1973
- Oxidation of glucose and fatty acids in normal and in A2-cell rich pancreatic islets isolated from guinea-pigsDiabetologia, 1972
- The effect of mannoheptulose on glucose- and pyruvate-stimulated oxygen uptake in normal mouse pancreatic isletsBiochimica et Biophysica Acta (BBA) - General Subjects, 1972
- Isolated mouse islets as a model for studying insulin releaseActa Diabetologica, 1971
- Glucose metabolism in mouse pancreatic isletsBiochemical Journal, 1970
- The dry mass of the pancreatic B-cells in relation to their content of secretion granulesJournal of Molecular Histology, 1968
- Effects of Carbohydrates on the Oxygen Consumption of Isolated Pancreatic Islets of MiceEndocrinology, 1967
- STUDIES IN OBESE‐HYPERGLYCEMIC MICE*Annals of the New York Academy of Sciences, 1965