Dihydrofolate reductase inhibition by 2,4-diaminotriazines: A structure-activity study

This publication has 27 references indexed in Scilit:

• Synthesis of the antileukemic compound N,N''-[5-[bis(2-chloroethyl)amino]-1,3-phenylene]bisurea
  Journal of Medicinal Chemistry, 1976
• Correlation analysis. Its application to the structure-activity relation of triazines inhibiting dihydrofolate reductase
  Journal of the American Chemical Society, 1975
• Steady-state enzyme kinetics with high-affinity substrates or inhibitors. A statistical treatment of dose–response curves
  Biochemical Journal, 1973
• Dihydrofolate Reductase
  Published by Elsevier ,1973
• The graphical determination of Km and Ki
  Biochemical Journal, 1972
• A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors
  Biochemical Journal, 1972
• Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors
  Biochimica et Biophysica Acta (BBA) - Enzymology, 1969
• Effect of substrate decomposition on the spectrophotometric assay of dihydrofolate reductase
  Analytical Biochemistry, 1967
• The Role of Dihydrofolic Reductase in the Metabolism of One-Carbon Units^*
  Biochemistry, 1963
• Chemical and Biological Studies on 1,2-Dihydro-s-triazines. II. Three-Component Synthesis¹
  The Journal of Organic Chemistry, 1956