Physiological Regulation of Uteroglobin/CCSP Expression
- 1 December 2000
- journal article
- review article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 923 (1) , 181-192
- https://doi.org/10.1111/j.1749-6632.2000.tb05529.x
Abstract
Uteroglobin/CCSP is expressed specifically in the Clara cells. This allows the gene to be used as a marker to identify the elements regulating the physiologic and cell‐specific expression of this gene. The regulation of UG/CCSP by IFN‐γ was shown to be at the level of the proximal promoter by the upregulation of HNF3β. This has allowed the determination of the factors responsible for the expression of UG/CCSP.Keywords
This publication has 52 references indexed in Scilit:
- Human Uteroglobin Gene: Structure, Subchromosomal Localization, and PolymorphismDNA and Cell Biology, 1997
- Binding of retinoids to uteroglobinFEBS Letters, 1994
- Cloning and Characterization of the Mouse Clara Cell-Specific 10-kDa Protein Gene: Comparison of the 5′-Flanking Region with the Human, Rat, and Rabbit GeneBiochemical and Biophysical Research Communications, 1993
- Localization of an estrogen receptor binding site near the promoter of the uteroglobin geneFEBS Letters, 1990
- Partial purification of a binding protein for polychlorinated biphenyls from rat lung cytosol: physicochemical and immunochemical characterizationBiochemistry, 1988
- Refinement of the C2221 crystal form of oxidized uteroglobin at 1.34 Å resolutionJournal of Molecular Biology, 1987
- Comparison of Nonciliated Tracheal Epithelial Cells in Six Mammalian Species: Ultrastructure and Population DensitiesExperimental Lung Research, 1983
- Hormonal control of uteroglobin secretion and preuteroglobin mRNA content in rabbit endometriumMolecular and Cellular Endocrinology, 1981
- Characterization of two new crystal forms of uteroglobinJournal of Molecular Biology, 1979
- The formation of granules in the bronchiolar Clara cells of the rat: 1. Electron microscopyJournal of Ultrastructure Research, 1974