THE INFLUENCE OF A SUSTAINED MONOCYTOSIS UPON THE ANTIBODY RESPONSE IN RABBITS TO VARIOUS ANTIGENS

Abstract
By means of periodic injections of a chloroform soluble, nontoxic, and non-antigenic lipid substance extracted from Listeria monocytogenes, it was possible to stimulate and maintain a high degree of monocytosis in the blood of rabbits for at least twenty days. Animals immunized with Salmonella typhosa, staphylococcus toxoid, and horse serum during the period of monocytosis gave considerably higher titers than did control animals in every case.

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