Tracheobronchial aspergillosis in a patient with AIDS treated with aerosolized amphotericin B combined with itraconazole
- 1 September 1996
- Vol. 39 (9-10) , 371-374
- https://doi.org/10.1111/j.1439-0507.1996.tb00156.x
Abstract
Summary. The clinical features of a tracheobronchial infection due to Aspergillus flavus in an AIDS patient with a normal neutrophil count is described. Diagnosis was made by culture and microscopic examination of biopsies obtained from bronchial vegetations seen at bronchoscopy. Radiographic examination of the neck revealed the presence of large endoluminal fungal masses. Initially the patient was treated with a combination of itraconazole, flucytosine and aerosolized amphotericin B, then only with itraconazole plus aerosolized amphotericin B. A good therapeutic response was observed.Zusammenfassung. Das klinische Bild einer tracheobronchialen Infektion, verursacht durch Aspergillus flavus bei einem AIDS‐Patienten mit normaler Leukozytenzahl, wird vorgestellt. Die Diagnose wurde mikroskopisch und kulturell aus Biopsiematerial von Bronchialbelägen gestellt. Im Nacken‐Röntgenbild waren endoluminale Pilzmassen nachweisbar. Der Patient wurde anfänglich mit einer Kombination von Itraconazol. Flucytosin und Amphotericin B‐Aerosol behandelt, später nur mit Itraconazol und Amphotericin B‐Aerosol. Der Patient sprach gut auf diese Therapie an.Keywords
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