The sialomucin content of colonic resection margins

Publisher Website
Google Scholar
Abstract
In a prospective trial, the resection margins of 130 patients who underwent apparently curative resection for colorectal cancers were examined. Sialomucin was markedly increased in 17.0% of proximal resection margins and 17.3% in distal resection margins. Clinical follow-up has demonstrated 4 patients who have developed local recurrence of their disease. Three of these patients had increased sialomucin staining in the resection margins at the time of initial surgery. High iron diamine-alcian blue staining of resection margin may identify those patients at risk of developing local recurrence of colorectal cancer or metachronous tumor following apparently curative resection.