Natural history of cervical epithelial abnormalities in patients with vulval warts. A colposcopic study.

Publisher Website
Google Scholar
Abstract
The natural history of intraepithelial abnormalities of the cervix associated with human papillomavirus infection was investigated in a prospective study of 50 women with vulval warts, of whom 28 had colposcopic evidence of a cervical epithelial abnormality and 22 a normal cervix. Of the 28 with a cervical abnormality, 26 were reexamined by colposcopy after 3 mo.; the epithelial abnormality had persisted in 23 women. Nineteen women who had initially shown abnormality by colposcopy were reexamined 6 mo. after their 1st attendance; the epithelial abnormality had persisted in 14 women. Of the 22 women who initially had a normal cervix, 19 were reexamined after 3 mo.; the cervix remained normal in 18, but an epithelial abnormality had developed in 1. Fourteen women who initially had a normal cervix were reexamined 6 mo. after their 1st attendance; the cervix was still normal in 11, but an epithelial abnormality had developed in 3. Colposcopically directed biopsy specimens were obtained from 21 women who showed an epithelial abnormality; of these, evidence of wart virus infection was present in 4, cervical intraepithelial neoplasia in 2, both conditions in 13 and no abnormality in 2. Thus, lesions of the cervix associated with wart virus infection show little evidence of short term regression.

This publication has 5 references indexed in Scilit: