Follicular Mucinosis

Abstract
IN 1957, Hermann Pinkus1 described a group of 6 patients with localized alopecia characterized histopathologically by mucin deposition within hair follicles. In the following years, the term follicular mucinosis (FM) proposed by Jablonska et al2 in 1959 slowly replaced alopecia mucinosa, the designation originally coined by Pinkus himself. Subsequent reports suggested that at least 2 distinct entities were encompassed under this diagnosis: one occurring in children and young adults without association with other cutaneous or extracutaneous diseases ("idiopathic" FM), the other occurring in elderly patients and associated with mycosis fungoides or Sézary syndrome ("lymphoma-associated" FM).3-13 In addition, progression of idiopathic FM into cutaneous T-cell lymphoma (CTCL) has been well documented in several cases.14-18

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