Cardiac Hypertrophy in Rats and Mice Given 3, 3', 5-Triiodo-L-Thyronine Orally
- 31 October 1958
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 195 (2) , 385-390
- https://doi.org/10.1152/ajplegacy.1958.195.2.385
Abstract
The giving of 3,3',5-triiodo-l-thyronine in the drinking water produces marked metabolic and circulatory changes. These effects produce hypertrophy of the heart. The water content of the hypertrophied hearts does not change. The hypertrophy of the heart is obtained in both rats and mice. In the rat, following removal of the T-3, there is a return of the heart to approximately the normal size.Keywords
This publication has 3 references indexed in Scilit:
- 3:5:3′-Triiodothyronine. 2. Physiological activityBiochemical Journal, 1953
- Influence of Thyroid Hormone on Respiration of Cardiac TissueAmerican Journal of Physiology-Legacy Content, 1952
- EXPERIMENTAL RENAL INSUFFICIENCY PRODUCED BY PARTIAL NEPHRECTOMYArchives of internal medicine (1960), 1933