PDZ Domains: Folding and Binding
- 1 July 2007
- journal article
- review article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 46 (30) , 8701-8708
- https://doi.org/10.1021/bi7008618
Abstract
The PDZ domain is one of the most common protein-protein interaction domains in humans, and it is found in all kingdoms of life. We will review recent progress in the understanding of biophysical aspects of PDZ domains with emphasis on the folding and binding reactions. Finally, we discuss an intriguing correlation between stability and binding of peptide for PDZ2 from PTP-BL.Keywords
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