CARDIOVASCULAR EFFECTS OF SECRETIN INFUSION IN MAN
- 1 January 1983
- journal article
- research article
- Vol. 43 (7) , 637-642
Abstract
Secretin infusion in man causes an increase in renal blood flow. The cardiovascular effects of the hormone were assessed. Secretin was infused at a rate of 2 CU/kg .cntdot. h to patients with angina pectoris and normal left ventricular function. Cardiac output increased by an average of 20%, the stroke volume increased and the total systemic resistance decreased. Systemic arterial pressure, heart rate and pulmonary capillary wedge pressure were unaltered. The results are compatible with a combined inotropic and vasodilating effect of the hormone. Secretin may have potential merits in the treatment of acute left ventricular failure.This publication has 1 reference indexed in Scilit: