Hypercalcaemia in B cell chronic lymphocytic leukaemia
- 1 August 1994
- journal article
- case report
- Published by Wiley in British Journal of Haematology
- Vol. 87 (4) , 856-858
- https://doi.org/10.1111/j.1365-2141.1994.tb06752.x
Abstract
Summary: Hypercalcaemia is common in some lymphoproliferative disorders such as myeloma or T‐cell leukaemialymphoma. but is rarely described in B cell chronic lymphocytic leukaemia (BCLL). We report the case of a patient with BCLL, hypercalcaemia and osteolytic bone lesions. Parathyroid hromone‐related protein (PTHrP) mRNA was identified by Northern blot analysis of liver. spleen and lymph node tumour samples. Serum levels of tumour necrosis factor alpha (TNFα) were increased.Keywords
This publication has 13 references indexed in Scilit:
- Production of tumor necrosis factor-alpha by B-cell chronic lymphocytic leukemia and hairy cell leukemia cells: considerations regarding bone remodeling in the chronic B-cell leukemias [letter]Blood, 1991
- Identification of an Up-Stream Promoter of the Human Parathyroid Hormone-Related Peptide GeneMolecular Endocrinology, 1990
- Hypercalcaemia and serum TNF-α in T-cell leukaemiaThe Lancet, 1990
- Expression of Messenger Ribonucleic Acids Encoding a Parathyroid Hormone-Like Peptide in Normal Human and Animal Tissues with Abnormal Expression in Human Parathyroid AdenomasMolecular Endocrinology, 1988
- TUMOUR NECROSIS FACTOR AS AN AUTOCRINE TUMOUR GROWTH FACTOR FOR CHRONIC B-CELL MALIGNANCIESThe Lancet, 1988
- Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy.Proceedings of the National Academy of Sciences, 1988
- Production of 1,25-dihydroxyvitamin D3 by human T cell lymphotrophic virus-I-transformed lymphocytes.Journal of Clinical Investigation, 1986
- Hypercalcaemia in chronic lymphatic leukaemiaPublished by Oxford University Press (OUP) ,1986
- Hypercalcaemia and osteolytic bone lesions in chronic lymphocytic leukaemia.BMJ, 1980
- Hypercalcemia associated with chronic lymphocytic leukemiaArchives of internal medicine (1960), 1979