Studies of Ineffective Erythropoiesis and Peripheral Haemolysis in Congenital Dyserythropoietic Anaemia Type II
- 1 October 1979
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 43 (2) , 243-250
- https://doi.org/10.1111/j.1365-2141.1979.tb03747.x
Abstract
Summary. Erythrokinetic parameters were estimated in six patients suffering from congenital dyserythropoietic anaemia type II (CDA II) by means of a mathematical model of iron kinetics. A wide variation in effectiveness of erythroid activity was observed, and a significant negative correlation was found between ineffective erythropoiesis and peripheral haemolysis. In four patients with prominent peripheral haemolysis, splenectomy was carried out. Marked improvement in their clinical condition and in haemoglobin level resulted.This publication has 23 references indexed in Scilit:
- Estimation of Ferrokinetic Parameters by a Mathematical Model in Patients with Primary Acquired Sideroblastic AnaemiaBritish Journal of Haematology, 1978
- Iron kinetics: Modelling and parameter estimation in normal and anemic statesComputers and Biomedical Research, 1978
- Ultrastruktur der erythroiden Zellen bei einer kongenitalen dyserythropoetischen An mie Typ IIAnnals of Hematology, 1977
- A simple method for simultaneous liquid scintillation counting of 59Fe and 51Cr in bloodThe International Journal of Applied Radiation and Isotopes, 1976
- The Measurement of 59Fe Clearance from the PlasmaScandinavian Journal of Haematology, 1976
- The Abnormal Surface Characteristics of the Red Blood Cell Membrane in Congenital Dyserythropoietic Anaemia Type II (HEMPAS)British Journal of Haematology, 1975
- Recommended Methods for Surface Counting to Determine Sites of Red‐Cell DestructionBritish Journal of Haematology, 1975
- Congenital Dyserythropoietic Anaemia Type IIActa Haematologica, 1974
- SURFACE COUNTING IN THE ASSESSMENT OF SITES OF RED CELL DESTRUCTIONBritish Journal of Haematology, 1970
- On the stochastic interpretation of cell survival curvesJournal of Theoretical Biology, 1962