EFFECT OF OXIDIZED REGENERATED CELLULOSE ON EXPERIMENTAL INTRAVASCULAR INFECTION

  • 1 January 1977
    • journal article
    • research article
    • Vol. 82  (5) , 576-579
Abstract
Two groups of dogs had aortotomies and insertion of a Teflon patch. One group had the area of the aorta with the patch wrapped with oxidized regenerated cellulose (ORC); the other group served as a control. Both groups of animals were infected with Staphylococcus aureus i.v. immediately after removal of aortic clamps. Animals which had ORC wrapping of the aorta had significantly lower bacterial counts at time of death than did the untreated group. This was measured from 1 h after challenge up to 30 days.

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