VLDL apoprotein secretion and apo‐B mRNA level in primary culture of cholesterol‐loaded rabbit hepatocytes
- 9 May 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 232 (1) , 103-106
- https://doi.org/10.1016/0014-5793(88)80395-8
Abstract
Incubation of cultured rabbit hepatocytes with β very low density lipoproteins (β‐VLDL) induces a dose‐dependent increase in cell cholesterol (CH) content and VLDL apoprotein (apo) B and E secretion without change in apo‐B mRNA level. These data suggest that β‐VLDL may exert a stimulatory effect on hepatic apo‐B production at the co‐translational and/or posttranslational level.Keywords
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