A rush to judgment on Th17
Open Access
- 30 June 2008
- journal article
- editorial
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 205 (7) , 1517-1522
- https://doi.org/10.1084/jem.20072066
Abstract
Some immunologists have characterized T helper (Th)17 T cells as the master mediators of tissue damage in a variety of pathological conditions. New data now demonstrate that Th1 and Th17 T cells are independently capable of inducing disease in two established models of autoimmunity. Thus, the role of Th17 cytokines as the central mediators of pathological tissue damage seems to require clarification.Keywords
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