Differences in Vitamin E Levels in Tissues of the Spontaneously Hypertensive and Wistar-Kyoto Rats

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Abstract
Tissue vitamin E levels were significantly lower in spontaneously hypertensive rats (SHR) than in the normotensive, genetically related Wistar/Kyoto (W/K). This difference was also observed when animals were given identical oral doses of vitamin E. The possible relationship of lower vitamin E tissue levels to lower immune responses in the SHR is discussed.